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pseudo-random number generator  (SAS institute)


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    Structured Review

    SAS institute pseudo-random number generator
    Pseudo Random Number Generator, supplied by SAS institute, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/pseudo-random+number+generator/pseudo+random+number+generator/pmc12198475-165-1-7
    Average 90 stars, based on 1 article reviews
    pseudo-random number generator - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    Sequencing:

    Article Title: Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age of 6 to 11 years
    Article Snippet: Random sequence generation (selection bias) , Low risk , Quote from publication: · "We used a stratified block randomization scheme to assign practices to one of the 3 study arms. Strata were based on the volume of children aged 6.0 to 12.9 with a BMI 95th percentile seen for well‐child visits at each site from April 2010 through March 2011. A biostatistician (KPK) blinded to the names of the practices ordered them on this characteristic, then introduced a false practice at a random spot within the order to make the number of "practices" evenly divisible by 3. Strata consisted of consecutive groups of three practices from this ordered list. He then used a pseudo‐random number generator in SAS 9.2 (SAS Institute, Cary NC) to assign one practice from each strata to each of the arms, with the exception that the false practice was deterministically assigned to the usual care arm. This resulted in 5 practices in each of the intervention arms and 4 in the usual care arm." Comment: randomisation process described.

    Article Title: Vitamin supplementation for preventing miscarriage
    Article Snippet: Pregnat women were randomly allocated in a 1:1:1:1 ratio in blocks of 12 based on a list of treatment numbers derived from a pseudo‐random number generated with SAS software.

    Article Title: Effects of vitamin and mineral supplementation during pregnancy on maternal, birth, child health and development outcomes in low‐ and middle‐income countries: A systematic review
    Article Snippet: SC was nutrition consultant for UNICEF China from 2001‐2002, and is now the liaison officer for UNICEF with the Ministry of Health Funding sources: United Nations Children's Fund (grant No YH101‐H12/03) through a co‐ operative agreement between UNICEF and the Centers for Disease Control and Prevention, Atlanta, US, and the National Natural Science of Foundation of China (grant No 30271131), Beijing, China Risk of bias table Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Quote: "The randomisation schedule was generated off site with a pseudo‐ random number generator in SAS" Comment: probably done Allocation concealment (selection bias) Low risk Quote: "The randomisation schedule was generated off site with a pseudo‐ random number generator in SAS version 6 (SAS Institute, Cary, NC).

    Article Title: Effectiveness of a hysteroscopic tissue removal system device for hysteroscopic myomectomy on patients' quality of life: a randomized clinical trial.
    Article Snippet: The randomization scheme was created using a pseudo-random number generator (i.e., the PLAN procedure within the SAS software, version 9.4 (SAS Institute Inc., Cary, NC) and consisted of random permuted blocks, having variable blocks of either size 2 or 4, with a 1:1 allocation to the treatments.

    Article Title: Effects of the SGLT2 inhibitor dapagliflozin in early Alzheimer's disease: A randomized controlled trial
    Article Snippet: The treatment order was determined using the SAS (Cary, NC) pseudo‐random number generator.

    Article Title: Multiple‐micronutrient supplementation for women during pregnancy
    Article Snippet: Random sequence generation (selection bias) , Low risk , Quote: "The randomisation schedule was generated off site with a pseudo‐random number generator in SAS". Comment: probably done.

    Article Title: Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding
    Article Snippet: Notes Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Participants were randomly assigned (1:1 ratio) to study groups using a pseudo-random number generator (PROC PLAN procedure in SAS) in randomly permuted blocks of 4, stratified by centre.

    Article Title: Effectiveness of focused meditation for patients with chronic low back pain-A randomized controlled clinical trial.
    Article Snippet: Objectives: We aimed to evaluate the effectiveness of an 8-week meditation program (focused meditation) in patients with chronic low-back pain.. Design: A randomized clinical trial was conducted on 68 patients (55 years;75% female) with chronic low-back pain who scored >40 mm on a 100 mm Visual-Analogue-Scale.. Subjects were allocated to an 8-week meditation program (focused meditation) with weekly 75 min classes or to a self-care exercise program with a wait-list offer for meditation.

    Selection:

    Article Title: Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age of 6 to 11 years
    Article Snippet: Random sequence generation (selection bias) , Low risk , Quote from publication: · "We used a stratified block randomization scheme to assign practices to one of the 3 study arms. Strata were based on the volume of children aged 6.0 to 12.9 with a BMI 95th percentile seen for well‐child visits at each site from April 2010 through March 2011. A biostatistician (KPK) blinded to the names of the practices ordered them on this characteristic, then introduced a false practice at a random spot within the order to make the number of "practices" evenly divisible by 3. Strata consisted of consecutive groups of three practices from this ordered list. He then used a pseudo‐random number generator in SAS 9.2 (SAS Institute, Cary NC) to assign one practice from each strata to each of the arms, with the exception that the false practice was deterministically assigned to the usual care arm. This resulted in 5 practices in each of the intervention arms and 4 in the usual care arm." Comment: randomisation process described.

    Article Title: Vitamin supplementation for preventing miscarriage
    Article Snippet: Pregnat women were randomly allocated in a 1:1:1:1 ratio in blocks of 12 based on a list of treatment numbers derived from a pseudo‐random number generated with SAS software.

    Article Title: Effects of vitamin and mineral supplementation during pregnancy on maternal, birth, child health and development outcomes in low‐ and middle‐income countries: A systematic review
    Article Snippet: SC was nutrition consultant for UNICEF China from 2001‐2002, and is now the liaison officer for UNICEF with the Ministry of Health Funding sources: United Nations Children's Fund (grant No YH101‐H12/03) through a co‐ operative agreement between UNICEF and the Centers for Disease Control and Prevention, Atlanta, US, and the National Natural Science of Foundation of China (grant No 30271131), Beijing, China Risk of bias table Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Quote: "The randomisation schedule was generated off site with a pseudo‐ random number generator in SAS" Comment: probably done Allocation concealment (selection bias) Low risk Quote: "The randomisation schedule was generated off site with a pseudo‐ random number generator in SAS version 6 (SAS Institute, Cary, NC).

    Article Title: Effectiveness of a hysteroscopic tissue removal system device for hysteroscopic myomectomy on patients' quality of life: a randomized clinical trial.
    Article Snippet: The randomization scheme was created using a pseudo-random number generator (i.e., the PLAN procedure within the SAS software, version 9.4 (SAS Institute Inc., Cary, NC) and consisted of random permuted blocks, having variable blocks of either size 2 or 4, with a 1:1 allocation to the treatments.

    Article Title: Effects of the SGLT2 inhibitor dapagliflozin in early Alzheimer's disease: A randomized controlled trial
    Article Snippet: The treatment order was determined using the SAS (Cary, NC) pseudo‐random number generator.

    Article Title: Multiple‐micronutrient supplementation for women during pregnancy
    Article Snippet: Random sequence generation (selection bias) , Low risk , Quote: "The randomisation schedule was generated off site with a pseudo‐random number generator in SAS". Comment: probably done.

    Article Title: Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding
    Article Snippet: Notes Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Participants were randomly assigned (1:1 ratio) to study groups using a pseudo-random number generator (PROC PLAN procedure in SAS) in randomly permuted blocks of 4, stratified by centre.

    Article Title: Effectiveness of focused meditation for patients with chronic low back pain-A randomized controlled clinical trial.
    Article Snippet: Objectives: We aimed to evaluate the effectiveness of an 8-week meditation program (focused meditation) in patients with chronic low-back pain.. Design: A randomized clinical trial was conducted on 68 patients (55 years;75% female) with chronic low-back pain who scored >40 mm on a 100 mm Visual-Analogue-Scale.. Subjects were allocated to an 8-week meditation program (focused meditation) with weekly 75 min classes or to a self-care exercise program with a wait-list offer for meditation.

    Control:

    Article Title: Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age of 6 to 11 years
    Article Snippet: Random sequence generation (selection bias) , Low risk , Quote from publication: · "We used a stratified block randomization scheme to assign practices to one of the 3 study arms. Strata were based on the volume of children aged 6.0 to 12.9 with a BMI 95th percentile seen for well‐child visits at each site from April 2010 through March 2011. A biostatistician (KPK) blinded to the names of the practices ordered them on this characteristic, then introduced a false practice at a random spot within the order to make the number of "practices" evenly divisible by 3. Strata consisted of consecutive groups of three practices from this ordered list. He then used a pseudo‐random number generator in SAS 9.2 (SAS Institute, Cary NC) to assign one practice from each strata to each of the arms, with the exception that the false practice was deterministically assigned to the usual care arm. This resulted in 5 practices in each of the intervention arms and 4 in the usual care arm." Comment: randomisation process described.

    Article Title: Vitamin supplementation for preventing miscarriage
    Article Snippet: Pregnat women were randomly allocated in a 1:1:1:1 ratio in blocks of 12 based on a list of treatment numbers derived from a pseudo‐random number generated with SAS software.

    Article Title: Effects of vitamin and mineral supplementation during pregnancy on maternal, birth, child health and development outcomes in low‐ and middle‐income countries: A systematic review
    Article Snippet: SC was nutrition consultant for UNICEF China from 2001‐2002, and is now the liaison officer for UNICEF with the Ministry of Health Funding sources: United Nations Children's Fund (grant No YH101‐H12/03) through a co‐ operative agreement between UNICEF and the Centers for Disease Control and Prevention, Atlanta, US, and the National Natural Science of Foundation of China (grant No 30271131), Beijing, China Risk of bias table Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Quote: "The randomisation schedule was generated off site with a pseudo‐ random number generator in SAS" Comment: probably done Allocation concealment (selection bias) Low risk Quote: "The randomisation schedule was generated off site with a pseudo‐ random number generator in SAS version 6 (SAS Institute, Cary, NC).

    Article Title: Effectiveness of a hysteroscopic tissue removal system device for hysteroscopic myomectomy on patients' quality of life: a randomized clinical trial.
    Article Snippet: The randomization scheme was created using a pseudo-random number generator (i.e., the PLAN procedure within the SAS software, version 9.4 (SAS Institute Inc., Cary, NC) and consisted of random permuted blocks, having variable blocks of either size 2 or 4, with a 1:1 allocation to the treatments.

    Article Title: Effects of the SGLT2 inhibitor dapagliflozin in early Alzheimer's disease: A randomized controlled trial
    Article Snippet: The treatment order was determined using the SAS (Cary, NC) pseudo‐random number generator.

    Article Title: Multiple‐micronutrient supplementation for women during pregnancy
    Article Snippet: Random sequence generation (selection bias) , Low risk , Quote: "The randomisation schedule was generated off site with a pseudo‐random number generator in SAS". Comment: probably done.

    Article Title: Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding
    Article Snippet: Notes Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Participants were randomly assigned (1:1 ratio) to study groups using a pseudo-random number generator (PROC PLAN procedure in SAS) in randomly permuted blocks of 4, stratified by centre.

    Article Title: Effectiveness of focused meditation for patients with chronic low back pain-A randomized controlled clinical trial.
    Article Snippet: Objectives: We aimed to evaluate the effectiveness of an 8-week meditation program (focused meditation) in patients with chronic low-back pain.. Design: A randomized clinical trial was conducted on 68 patients (55 years;75% female) with chronic low-back pain who scored >40 mm on a 100 mm Visual-Analogue-Scale.. Subjects were allocated to an 8-week meditation program (focused meditation) with weekly 75 min classes or to a self-care exercise program with a wait-list offer for meditation.

    Generated:

    Article Title: Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age of 6 to 11 years
    Article Snippet: Random sequence generation (selection bias) , Low risk , Quote from publication: · "We used a stratified block randomization scheme to assign practices to one of the 3 study arms. Strata were based on the volume of children aged 6.0 to 12.9 with a BMI 95th percentile seen for well‐child visits at each site from April 2010 through March 2011. A biostatistician (KPK) blinded to the names of the practices ordered them on this characteristic, then introduced a false practice at a random spot within the order to make the number of "practices" evenly divisible by 3. Strata consisted of consecutive groups of three practices from this ordered list. He then used a pseudo‐random number generator in SAS 9.2 (SAS Institute, Cary NC) to assign one practice from each strata to each of the arms, with the exception that the false practice was deterministically assigned to the usual care arm. This resulted in 5 practices in each of the intervention arms and 4 in the usual care arm." Comment: randomisation process described.

    Article Title: Vitamin supplementation for preventing miscarriage
    Article Snippet: Pregnat women were randomly allocated in a 1:1:1:1 ratio in blocks of 12 based on a list of treatment numbers derived from a pseudo‐random number generated with SAS software.

    Article Title: Effects of vitamin and mineral supplementation during pregnancy on maternal, birth, child health and development outcomes in low‐ and middle‐income countries: A systematic review
    Article Snippet: SC was nutrition consultant for UNICEF China from 2001‐2002, and is now the liaison officer for UNICEF with the Ministry of Health Funding sources: United Nations Children's Fund (grant No YH101‐H12/03) through a co‐ operative agreement between UNICEF and the Centers for Disease Control and Prevention, Atlanta, US, and the National Natural Science of Foundation of China (grant No 30271131), Beijing, China Risk of bias table Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Quote: "The randomisation schedule was generated off site with a pseudo‐ random number generator in SAS" Comment: probably done Allocation concealment (selection bias) Low risk Quote: "The randomisation schedule was generated off site with a pseudo‐ random number generator in SAS version 6 (SAS Institute, Cary, NC).

    Article Title: Effectiveness of a hysteroscopic tissue removal system device for hysteroscopic myomectomy on patients' quality of life: a randomized clinical trial.
    Article Snippet: The randomization scheme was created using a pseudo-random number generator (i.e., the PLAN procedure within the SAS software, version 9.4 (SAS Institute Inc., Cary, NC) and consisted of random permuted blocks, having variable blocks of either size 2 or 4, with a 1:1 allocation to the treatments.

    Article Title: Effects of the SGLT2 inhibitor dapagliflozin in early Alzheimer's disease: A randomized controlled trial
    Article Snippet: The treatment order was determined using the SAS (Cary, NC) pseudo‐random number generator.

    Article Title: Multiple‐micronutrient supplementation for women during pregnancy
    Article Snippet: Random sequence generation (selection bias) , Low risk , Quote: "The randomisation schedule was generated off site with a pseudo‐random number generator in SAS". Comment: probably done.

    Article Title: Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding
    Article Snippet: Notes Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Participants were randomly assigned (1:1 ratio) to study groups using a pseudo-random number generator (PROC PLAN procedure in SAS) in randomly permuted blocks of 4, stratified by centre.

    Article Title: Effectiveness of focused meditation for patients with chronic low back pain-A randomized controlled clinical trial.
    Article Snippet: Objectives: We aimed to evaluate the effectiveness of an 8-week meditation program (focused meditation) in patients with chronic low-back pain.. Design: A randomized clinical trial was conducted on 68 patients (55 years;75% female) with chronic low-back pain who scored >40 mm on a 100 mm Visual-Analogue-Scale.. Subjects were allocated to an 8-week meditation program (focused meditation) with weekly 75 min classes or to a self-care exercise program with a wait-list offer for meditation.

    Blocking Assay:

    Article Title: Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age of 6 to 11 years
    Article Snippet: Random sequence generation (selection bias) , Low risk , Quote from publication: · "We used a stratified block randomization scheme to assign practices to one of the 3 study arms. Strata were based on the volume of children aged 6.0 to 12.9 with a BMI 95th percentile seen for well‐child visits at each site from April 2010 through March 2011. A biostatistician (KPK) blinded to the names of the practices ordered them on this characteristic, then introduced a false practice at a random spot within the order to make the number of "practices" evenly divisible by 3. Strata consisted of consecutive groups of three practices from this ordered list. He then used a pseudo‐random number generator in SAS 9.2 (SAS Institute, Cary NC) to assign one practice from each strata to each of the arms, with the exception that the false practice was deterministically assigned to the usual care arm. This resulted in 5 practices in each of the intervention arms and 4 in the usual care arm." Comment: randomisation process described.

    Article Title: Vitamin supplementation for preventing miscarriage
    Article Snippet: Pregnat women were randomly allocated in a 1:1:1:1 ratio in blocks of 12 based on a list of treatment numbers derived from a pseudo‐random number generated with SAS software.

    Article Title: Effects of vitamin and mineral supplementation during pregnancy on maternal, birth, child health and development outcomes in low‐ and middle‐income countries: A systematic review
    Article Snippet: SC was nutrition consultant for UNICEF China from 2001‐2002, and is now the liaison officer for UNICEF with the Ministry of Health Funding sources: United Nations Children's Fund (grant No YH101‐H12/03) through a co‐ operative agreement between UNICEF and the Centers for Disease Control and Prevention, Atlanta, US, and the National Natural Science of Foundation of China (grant No 30271131), Beijing, China Risk of bias table Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Quote: "The randomisation schedule was generated off site with a pseudo‐ random number generator in SAS" Comment: probably done Allocation concealment (selection bias) Low risk Quote: "The randomisation schedule was generated off site with a pseudo‐ random number generator in SAS version 6 (SAS Institute, Cary, NC).

    Article Title: Effectiveness of a hysteroscopic tissue removal system device for hysteroscopic myomectomy on patients' quality of life: a randomized clinical trial.
    Article Snippet: The randomization scheme was created using a pseudo-random number generator (i.e., the PLAN procedure within the SAS software, version 9.4 (SAS Institute Inc., Cary, NC) and consisted of random permuted blocks, having variable blocks of either size 2 or 4, with a 1:1 allocation to the treatments.

    Article Title: Effects of the SGLT2 inhibitor dapagliflozin in early Alzheimer's disease: A randomized controlled trial
    Article Snippet: The treatment order was determined using the SAS (Cary, NC) pseudo‐random number generator.

    Article Title: Multiple‐micronutrient supplementation for women during pregnancy
    Article Snippet: Random sequence generation (selection bias) , Low risk , Quote: "The randomisation schedule was generated off site with a pseudo‐random number generator in SAS". Comment: probably done.

    Article Title: Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding
    Article Snippet: Notes Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Participants were randomly assigned (1:1 ratio) to study groups using a pseudo-random number generator (PROC PLAN procedure in SAS) in randomly permuted blocks of 4, stratified by centre.

    Article Title: Effectiveness of focused meditation for patients with chronic low back pain-A randomized controlled clinical trial.
    Article Snippet: Objectives: We aimed to evaluate the effectiveness of an 8-week meditation program (focused meditation) in patients with chronic low-back pain.. Design: A randomized clinical trial was conducted on 68 patients (55 years;75% female) with chronic low-back pain who scored >40 mm on a 100 mm Visual-Analogue-Scale.. Subjects were allocated to an 8-week meditation program (focused meditation) with weekly 75 min classes or to a self-care exercise program with a wait-list offer for meditation.

    Activity Assay:

    Article Title: Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age of 6 to 11 years
    Article Snippet: Random sequence generation (selection bias) , Low risk , Quote from publication: · "We used a stratified block randomization scheme to assign practices to one of the 3 study arms. Strata were based on the volume of children aged 6.0 to 12.9 with a BMI 95th percentile seen for well‐child visits at each site from April 2010 through March 2011. A biostatistician (KPK) blinded to the names of the practices ordered them on this characteristic, then introduced a false practice at a random spot within the order to make the number of "practices" evenly divisible by 3. Strata consisted of consecutive groups of three practices from this ordered list. He then used a pseudo‐random number generator in SAS 9.2 (SAS Institute, Cary NC) to assign one practice from each strata to each of the arms, with the exception that the false practice was deterministically assigned to the usual care arm. This resulted in 5 practices in each of the intervention arms and 4 in the usual care arm." Comment: randomisation process described.

    Article Title: Vitamin supplementation for preventing miscarriage
    Article Snippet: Pregnat women were randomly allocated in a 1:1:1:1 ratio in blocks of 12 based on a list of treatment numbers derived from a pseudo‐random number generated with SAS software.

    Article Title: Effects of vitamin and mineral supplementation during pregnancy on maternal, birth, child health and development outcomes in low‐ and middle‐income countries: A systematic review
    Article Snippet: SC was nutrition consultant for UNICEF China from 2001‐2002, and is now the liaison officer for UNICEF with the Ministry of Health Funding sources: United Nations Children's Fund (grant No YH101‐H12/03) through a co‐ operative agreement between UNICEF and the Centers for Disease Control and Prevention, Atlanta, US, and the National Natural Science of Foundation of China (grant No 30271131), Beijing, China Risk of bias table Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Quote: "The randomisation schedule was generated off site with a pseudo‐ random number generator in SAS" Comment: probably done Allocation concealment (selection bias) Low risk Quote: "The randomisation schedule was generated off site with a pseudo‐ random number generator in SAS version 6 (SAS Institute, Cary, NC).

    Article Title: Effectiveness of a hysteroscopic tissue removal system device for hysteroscopic myomectomy on patients' quality of life: a randomized clinical trial.
    Article Snippet: The randomization scheme was created using a pseudo-random number generator (i.e., the PLAN procedure within the SAS software, version 9.4 (SAS Institute Inc., Cary, NC) and consisted of random permuted blocks, having variable blocks of either size 2 or 4, with a 1:1 allocation to the treatments.

    Article Title: Effects of the SGLT2 inhibitor dapagliflozin in early Alzheimer's disease: A randomized controlled trial
    Article Snippet: The treatment order was determined using the SAS (Cary, NC) pseudo‐random number generator.

    Article Title: Multiple‐micronutrient supplementation for women during pregnancy
    Article Snippet: Random sequence generation (selection bias) , Low risk , Quote: "The randomisation schedule was generated off site with a pseudo‐random number generator in SAS". Comment: probably done.

    Article Title: Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding
    Article Snippet: Notes Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Participants were randomly assigned (1:1 ratio) to study groups using a pseudo-random number generator (PROC PLAN procedure in SAS) in randomly permuted blocks of 4, stratified by centre.

    Article Title: Effectiveness of focused meditation for patients with chronic low back pain-A randomized controlled clinical trial.
    Article Snippet: Objectives: We aimed to evaluate the effectiveness of an 8-week meditation program (focused meditation) in patients with chronic low-back pain.. Design: A randomized clinical trial was conducted on 68 patients (55 years;75% female) with chronic low-back pain who scored >40 mm on a 100 mm Visual-Analogue-Scale.. Subjects were allocated to an 8-week meditation program (focused meditation) with weekly 75 min classes or to a self-care exercise program with a wait-list offer for meditation.

    Diagnostic Assay:

    Article Title: Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age of 6 to 11 years
    Article Snippet: Random sequence generation (selection bias) , Low risk , Quote from publication: · "We used a stratified block randomization scheme to assign practices to one of the 3 study arms. Strata were based on the volume of children aged 6.0 to 12.9 with a BMI 95th percentile seen for well‐child visits at each site from April 2010 through March 2011. A biostatistician (KPK) blinded to the names of the practices ordered them on this characteristic, then introduced a false practice at a random spot within the order to make the number of "practices" evenly divisible by 3. Strata consisted of consecutive groups of three practices from this ordered list. He then used a pseudo‐random number generator in SAS 9.2 (SAS Institute, Cary NC) to assign one practice from each strata to each of the arms, with the exception that the false practice was deterministically assigned to the usual care arm. This resulted in 5 practices in each of the intervention arms and 4 in the usual care arm." Comment: randomisation process described.

    Article Title: Vitamin supplementation for preventing miscarriage
    Article Snippet: Pregnat women were randomly allocated in a 1:1:1:1 ratio in blocks of 12 based on a list of treatment numbers derived from a pseudo‐random number generated with SAS software.

    Article Title: Effects of vitamin and mineral supplementation during pregnancy on maternal, birth, child health and development outcomes in low‐ and middle‐income countries: A systematic review
    Article Snippet: SC was nutrition consultant for UNICEF China from 2001‐2002, and is now the liaison officer for UNICEF with the Ministry of Health Funding sources: United Nations Children's Fund (grant No YH101‐H12/03) through a co‐ operative agreement between UNICEF and the Centers for Disease Control and Prevention, Atlanta, US, and the National Natural Science of Foundation of China (grant No 30271131), Beijing, China Risk of bias table Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Quote: "The randomisation schedule was generated off site with a pseudo‐ random number generator in SAS" Comment: probably done Allocation concealment (selection bias) Low risk Quote: "The randomisation schedule was generated off site with a pseudo‐ random number generator in SAS version 6 (SAS Institute, Cary, NC).

    Article Title: Effectiveness of a hysteroscopic tissue removal system device for hysteroscopic myomectomy on patients' quality of life: a randomized clinical trial.
    Article Snippet: The randomization scheme was created using a pseudo-random number generator (i.e., the PLAN procedure within the SAS software, version 9.4 (SAS Institute Inc., Cary, NC) and consisted of random permuted blocks, having variable blocks of either size 2 or 4, with a 1:1 allocation to the treatments.

    Article Title: Effects of the SGLT2 inhibitor dapagliflozin in early Alzheimer's disease: A randomized controlled trial
    Article Snippet: The treatment order was determined using the SAS (Cary, NC) pseudo‐random number generator.

    Article Title: Multiple‐micronutrient supplementation for women during pregnancy
    Article Snippet: Random sequence generation (selection bias) , Low risk , Quote: "The randomisation schedule was generated off site with a pseudo‐random number generator in SAS". Comment: probably done.

    Article Title: Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding
    Article Snippet: Notes Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Participants were randomly assigned (1:1 ratio) to study groups using a pseudo-random number generator (PROC PLAN procedure in SAS) in randomly permuted blocks of 4, stratified by centre.

    Article Title: Effectiveness of focused meditation for patients with chronic low back pain-A randomized controlled clinical trial.
    Article Snippet: Objectives: We aimed to evaluate the effectiveness of an 8-week meditation program (focused meditation) in patients with chronic low-back pain.. Design: A randomized clinical trial was conducted on 68 patients (55 years;75% female) with chronic low-back pain who scored >40 mm on a 100 mm Visual-Analogue-Scale.. Subjects were allocated to an 8-week meditation program (focused meditation) with weekly 75 min classes or to a self-care exercise program with a wait-list offer for meditation.

    Derivative Assay:

    Article Title: Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age of 6 to 11 years
    Article Snippet: Random sequence generation (selection bias) , Low risk , Quote from publication: · "We used a stratified block randomization scheme to assign practices to one of the 3 study arms. Strata were based on the volume of children aged 6.0 to 12.9 with a BMI 95th percentile seen for well‐child visits at each site from April 2010 through March 2011. A biostatistician (KPK) blinded to the names of the practices ordered them on this characteristic, then introduced a false practice at a random spot within the order to make the number of "practices" evenly divisible by 3. Strata consisted of consecutive groups of three practices from this ordered list. He then used a pseudo‐random number generator in SAS 9.2 (SAS Institute, Cary NC) to assign one practice from each strata to each of the arms, with the exception that the false practice was deterministically assigned to the usual care arm. This resulted in 5 practices in each of the intervention arms and 4 in the usual care arm." Comment: randomisation process described.

    Article Title: Vitamin supplementation for preventing miscarriage
    Article Snippet: Pregnat women were randomly allocated in a 1:1:1:1 ratio in blocks of 12 based on a list of treatment numbers derived from a pseudo‐random number generated with SAS software.

    Article Title: Effects of vitamin and mineral supplementation during pregnancy on maternal, birth, child health and development outcomes in low‐ and middle‐income countries: A systematic review
    Article Snippet: SC was nutrition consultant for UNICEF China from 2001‐2002, and is now the liaison officer for UNICEF with the Ministry of Health Funding sources: United Nations Children's Fund (grant No YH101‐H12/03) through a co‐ operative agreement between UNICEF and the Centers for Disease Control and Prevention, Atlanta, US, and the National Natural Science of Foundation of China (grant No 30271131), Beijing, China Risk of bias table Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Quote: "The randomisation schedule was generated off site with a pseudo‐ random number generator in SAS" Comment: probably done Allocation concealment (selection bias) Low risk Quote: "The randomisation schedule was generated off site with a pseudo‐ random number generator in SAS version 6 (SAS Institute, Cary, NC).

    Article Title: Effectiveness of a hysteroscopic tissue removal system device for hysteroscopic myomectomy on patients' quality of life: a randomized clinical trial.
    Article Snippet: The randomization scheme was created using a pseudo-random number generator (i.e., the PLAN procedure within the SAS software, version 9.4 (SAS Institute Inc., Cary, NC) and consisted of random permuted blocks, having variable blocks of either size 2 or 4, with a 1:1 allocation to the treatments.

    Article Title: Effects of the SGLT2 inhibitor dapagliflozin in early Alzheimer's disease: A randomized controlled trial
    Article Snippet: The treatment order was determined using the SAS (Cary, NC) pseudo‐random number generator.

    Article Title: Multiple‐micronutrient supplementation for women during pregnancy
    Article Snippet: Random sequence generation (selection bias) , Low risk , Quote: "The randomisation schedule was generated off site with a pseudo‐random number generator in SAS". Comment: probably done.

    Article Title: Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding
    Article Snippet: Notes Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Participants were randomly assigned (1:1 ratio) to study groups using a pseudo-random number generator (PROC PLAN procedure in SAS) in randomly permuted blocks of 4, stratified by centre.

    Article Title: Effectiveness of focused meditation for patients with chronic low back pain-A randomized controlled clinical trial.
    Article Snippet: Objectives: We aimed to evaluate the effectiveness of an 8-week meditation program (focused meditation) in patients with chronic low-back pain.. Design: A randomized clinical trial was conducted on 68 patients (55 years;75% female) with chronic low-back pain who scored >40 mm on a 100 mm Visual-Analogue-Scale.. Subjects were allocated to an 8-week meditation program (focused meditation) with weekly 75 min classes or to a self-care exercise program with a wait-list offer for meditation.



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